Therapeutics for combating the increasing bacterial resistance to antibiotics

Small molecule drug development

Analgesic pharmaceuticals
Acquired by Cubist Pharmaceuticals, Inc.
NASDAQ: CBST

Cancer therapies addressing cellular metabolism

Enhanced potency, tolerability and pharmacology of protein based therapeutics

RNA interference-based pharmaceuticals

Chemical intermediate sales and chemistry outsourcing

Live attenuated vaccines including FluMist
Acquired by MedImmune, Inc.
NASDAQ: MEDI

Biopharmaceutical firm developing therapeutic targeted nanoparticles

Gene therapies for childhood cerebral adrenoleukodystrophy (CCALD) and beta-thalassemia/sickle cell anemia

Pioneer in microfluidics ("lab on a chip") for research instrumentation and drug screening

Acquired by PerkinElmer, Inc.
NYSE: PKI

"Directed-evolution" technology platform employing molecular biology to synthesize nanostructures and advanced materials for use in electronics

New drug development technology enabling drugs to be switched from injectable to oral, creating new indications or improved labels

Chemical synthesis platform using DNA-programmed chemistry to develop synthetic macrocycle drugs called Ensemblins™

Adult stem cell biology

Gene therapy for cardiovascular disease and cancer

MicroRNA therapeutics

Sourcing drug discovery technology in U.S. and China

Discovery of small molecule drugs that interfere with apoptosis
Acquired by Pfizer
NYSE: PFE

Biotherapeutics to address unmet medical needs of critically ill patients

Fiber optic arrays for use in genomics

Building the next generation of biotech companies by providing resources critical to the achievement of scientific proof-of-concept

Aesthetic and dermatologic prescriptive therapies

Mitochondrial biology platform for discovery of small molecules related to diseases/conditions with abnormal cell activity

Technology utilizing nanowires, nanorods and nanocrystals with applications in electronics, biology, chemistry and quantum computing

Pharmaceuticals for intractable pain relief

Treatments for neurodegenerative diseases and behavioral disorders
Acquired by Omeros Corp.
NASDAQ: OMER

Pharmaco Surgery™ drug platform to reduce trauma from surgical and medical procedures

Cancer therapeutics that disrupt signaling pathways between tumors and the immune system

Intracellular biotherapeutics platform to enhance drug delivery

siRNA drug delivery technology

Inhaled therapeutics for respiratory disease and infections

GPCR drug discovery and development
NASDAQ: RCPT

Algae-based fuel as drop-in replacement for gasoline, diesel and jet fuel

Fluid-retaining polymers for therapeutics to treat kidney disease and other conditions

Human monoclonal antibody platform with multiple therapeutic product candidates

Alternate antibody scaffold platform company
Acquired by Emergent BioSolutions, Inc.
NYSE: EBS

Vaccine technology platform company enabling the development of thermostable and oral vaccines

Developing immunoregulatory therapies based on innate immunity

Virology-based platform for improved identification and validation of cell targets for therapeutic drug development

Immune therapy for cancer
Merged with Cyclacel Group plc
NASDAQ: CYCC

Enhanced drug delivery

Monoclonal antibody development platform